vestnik-bio-msuВестник Московского университета. Серия 16. БиологияVestnik Moskovskogo universiteta. Seriya 16. Biologiya0137-0952Lomonosov Moscow State University, School of Biologyvestnik-bio-msu-1135Research ArticleОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕRESEARCH ARTICLEСравнительное исследование динамики материнского поведения крыс Вистар и крыс линии ГК с предрасположенностью к кататоническим реакциямA comparative study of dynamics of maternal behavior in Wistar rats and rats selected for predisposition to catatonic reactions (GC rats)https://orcid.org/0000-0002-2168-8989ПрокудинаО. И.ProkudinaO. I.

 канд. биол. наук, науч. сотр.

Тел.: 8-383-363-49-63

 Россия, 630090, г. Новосибирск, просп. Академика Лаврентьева, д. 10 

10 Lavrentyeva pr., Novosibirsk, 630090, Russia

petrenko@bionet.nsc.ruЛаборатория эволюционной генетики, Институт цитологии и генетики, СО РАНРоссияLaboratory of Evolutionary Genetics, Institute of Cytology and Genetics, Siberian Branch of Russian Academy of SciencesRussian Federation202215062022772130–137Copyright © Прокудина О.И., 20222022Прокудина О.И.Prokudina O.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://vestnik-bio-msu.elpub.ru/jour/article/view/1135

Материнское поведение является важным фактором, влияющим на развитие потомства у млекопитающих. Особенности материнского поведения в ранний период онтогенеза могут оказывать стойкое влияние на ряд поведенческих и физиологических характеристик потомков во взрослом возрасте. В данной работе исследовали материнское поведение крыс линии ГК (от слов «генетические кататоники») и контрольных крыс Вистар c 1-х по 20-е сут после родов. Наблюдения проводили в домашней клетке в разное время суток с помощью автоматизированной системы видеорегистрации без присутствия экспериментатора. Показано, что самки линии ГК чаще бывали в гнезде и чаще кормили детенышей по сравнению с самками крыс Вистар. Кормящие самки Вистар чаще «отдыхали» вне гнезда, реже манипулировали гнездовым материалом и реже ухаживали за своей шерстью в течение суток. Изменение параметров материнского поведения по мере взросления потомства имело сходную динамику у обеих линий. При сравнении активности крыс в светлое и темное время суток обнаружена бóльшая активность вне гнезда в ночное время у самок линии ГК. Предполагается, что отличия в материнском поведении крыс кататонической линии могут быть обусловлены большей тревожностью крыс линии ГК по сравнению с контрольными крысами.

 Maternal behavior is an important factor for the offspring development in mammals. Particular traits of maternal behavior in the early ontogenesis may have a lasting effect on a number of behavioral and physiological parameters of offspring in their adulthood. In this study, we examined the maternal behavior of GC rats (GC stands for “genetic catatonics”) and control Wistar rats from the 1st to the 20th day after birth. Observations were carried out in a home cage during the day using an automated video recording system without the experimenter’s presence. GC female rats were found in the nest and nurse pups more often, as compared to the female Wistar rats. Wistar female rats “rested” outside the nest more often during the day, along withless frequent manipulations with nest material and less frequent self-grooming. The change in the frequency of maternal behavior patterns as the offspring matures has similar dynamics in both rat strains. When comparing activity in the light and dark phases of the light/dark cycle, we found that GC females had a greater activity outside the nest at night. We assume that distinguished maternal behavior of catatonic rats may be due to greater anxiety in GC rats, as compared to control rats. 

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The authors declare that there are no conflicts of interest present.