vestnik-bio-msuВестник Московского университета. Серия 16. БиологияVestnik Moskovskogo universiteta. Seriya 16. Biologiya0137-0952Lomonosov Moscow State University, School of Biology10.1234/XXXX-XXXX-2013-3-3-8vestnik-bio-msu-21Research ArticleФизиологияPhysiologyМЕЛАТОНИН И ДЕТОРОЖДЕНИЕ. ЧАСТЬ 1. ДОИМПЛАНТАЦИОННЫЙ ПЕРИОД И ИМПЛАНТАЦИЯMELATONIN AND CHILD-BEARING. PART 1. PREIMPLANTATION PERIOD AND IMPLANTATIONМолчановА. Ю.MolchanovA. Yu.

науч. сотр. кафедры эмбриологии МГУ. Тел.: 8-495-939-14-19

img@genebee.msu.suИвановскаяМ. Г.IvanovskayaM. G.

канд. хим. наук, ст. науч. сотр. Института физико-химической биологии им. Белозерского МГУ имени М.В. Ломоносова. Тел.: 8-916-693-51-72

img@genebee.msu.suНИИ физико-химической биологии им. А.Н. Белозерского МГУ имени М.В. Ломоносова, 119991, г. Москва.Россия2013300420150338Copyright © Молчанов А.Ю., Ивановская М.Г., 20152015Молчанов А.Ю., Ивановская М.Г.Molchanov A.Y., Ivanovskaya M.G.This work is licensed under a Creative Commons Attribution 4.0 License.https://vestnik-bio-msu.elpub.ru/jour/article/view/21

Мелатонин (М) — гормон, вырабатываемый у наземных позвоночных и человека в эндокринной железе — эпифизе. Установлено, что одной из основных функций М является синхронизация работы всех органов, регуляция сезонных и суточных ритмов их физиологической активности. Функция синхронизации и ритмовождения осуществляется в соответствии с суточным ритмом экспрессии М, зависящим от продолжительности дня и ночи. М способен влиять на рост, развитие и физиологическую активность различных типов клеток подобно ростовым факторам, воздействуя на механизмы сигнальных путей и каскадов. Подтверждено, что процессы зачатия, беременности и деторождения напрямую зависят от ритма и профиля секреции эпифизарного гормона М в организме. В данном обзоре предпринята попытка объединить имеющиеся литературные данные об участии М в различных физиологических процессах в течение доимплантационного и постимплантационного периодов жизни организма, его позитивном и негативном воздействии на этапах полового созревания.

Melatonin (M) — a hormone developed at land vertebrata and human in endocrine gland — pineal. It is established that one of the main functions M is synchronization of work of all bodies, regulation of seasonal and daily rhythms of their physiological activity. Function of synchronization and regulation of the rhythm is carried out according to a daily rhythm of an expression to the Mdepending on day and night length. The M is capable to influence growth, development and physiological activity of varios types of cell is similar to growth factors, influencing mechanisms of signaling pathways and cascades. It is confirmed that processes of conception, pregnancy and child-bearing directly depend on a rhythm an a profile of secretion of a pineal hormone of M in a organism. In this reveiew attempt to unite available in literary data of participation of M in various physiological processes durind preimplantation and post-implantation periods of life of an organism is undertaken, its positive and negative effects on puberty stages, gametogenese, fertilisation and implantation.

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The authors declare that there are no conflicts of interest present.