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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vestnik-bio-msu</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник Московского университета. Серия 16. Биология</journal-title><trans-title-group xml:lang="en"><trans-title>Vestnik Moskovskogo universiteta. Seriya 16. Biologiya</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0137-0952</issn><publisher><publisher-name>Lomonosov Moscow State University,  School of Biology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.1234/XXXX-XXXX-2012-4-7-9</article-id><article-id custom-type="elpub" pub-id-type="custom">vestnik-bio-msu-67</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Физиология</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Physiology</subject></subj-group></article-categories><title-group><article-title>КЛЕТОЧНЫЙ КАННИБАЛИЗМ В КУЛЬТУРЕ КЛЕТОК ЭПИДЕРМОИДНОЙ КАРЦИНОМЫ ЧЕЛОВЕКА А431</article-title><trans-title-group xml:lang="en"><trans-title>CELL CANNIBALISM IN CELL CULTURE OF HUMAN EPIDERMOID CARCINOMA A431</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гаранина</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Garanina</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>студентка кафедры клеточной биологии и гистологии биологического факультета МГУ. Тел.: 8-903-110-28-65</p></bio><email xlink:type="simple">anastasiacit@gmail.com</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Савицкая</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Savitskaya</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирантка кафедры клеточной биологии и гистологии биологического факультета МГУ. Тел.: 8-903-574-56-21</p></bio><email xlink:type="simple">nakomis@mail.ru</email></contrib></contrib-group><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>19</day><month>05</month><year>2015</year></pub-date><volume>0</volume><issue>4</issue><fpage>7</fpage><lpage>9</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гаранина А.С., Савицкая М.А., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Гаранина А.С., Савицкая М.А.</copyright-holder><copyright-holder xml:lang="en">Garanina A.S., Savitskaya M.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vestnik-bio-msu.elpub.ru/jour/article/view/67">https://vestnik-bio-msu.elpub.ru/jour/article/view/67</self-uri><abstract><p>В работе определены отдельные этапы процесса поглощения клетки клеткой, происходящего спонтанно в культуре эпидермоидной карциномы человека А431. Показано, что клеточный каннибализм (КК) сопровождается изменениями морфологии клетки-мишени внедрения и “клетки-жертвы” и что деградация последней происходит путем активации лизосом обеих клеток.</p></abstract><trans-abstract xml:lang="en"><p>We determined certain stages of spontaneous formation of “cell-in-cell” structures in A431 cell line. Cell cannibalism was accompanied with morphological alterations in host and internalized cells and lisosome-mediated degradation of internalized cell.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>культура клеток А431</kwd><kwd>клеточный каннибализм</kwd><kwd>механизмы.</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cell culture A431</kwd><kwd>cell cannibalism</kwd><kwd>mechanisms.</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Humble J.G., Jayne W.H.W., Pulvertaft R.J.V. 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