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PILOT STUDY OF A POTENTIAL GEROPROTECTOR, “QUINTON MARINE PLASMA”, IN EXPERIMENTS ON CULTURED CELLS

https://doi.org/10.1234/XXXX-XXXX-2015-1-9-13

Abstract

Effect of isotonic “Quinton Marine Plasma” (QMP) solution on the growth and “stationary phase aging” (accumulation of “age” changes in cultured cells during cell proliferation slowing down within a single passage and subsequent “aging” in the stationary phase of growth) of transformed Chinese hamster cells was studied. No positive effects of QMP on the studied viability indexes of the cultured cells were found in all the experiments. It is assumed that QMP, like many other potential anti-aging agents the authors studied recently (2,4-dinitrophenol in concentrations that provide mild uncoupling, the essential oil of oregano, hydrated C60-fullerene, etc.), can demonstrate its beneficial effect only at the level of the whole organism, triggering neurohumoral mechanisms that are not present in cytological model systems.

About the Authors

A. N. Khokhlov

Russian Federation


G. V. Morgunova

Russian Federation


T. S. Ryndina

Russian Federation


F. Coll
Квинтон Лабораториз, С.Л.”, пров. Аликанте, г. Кош, кв. Вирхен дель Кармен, ул. Аснар 6, 033350 Испания (Laboratories Quinton, S.L., Aznar Street 6, PI Virgen del Carmen, 033350 Cox, Alicante, Spain).
Russian Federation


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Review

For citations:


Khokhlov A.N., Morgunova G.V., Ryndina T.S., Coll F. PILOT STUDY OF A POTENTIAL GEROPROTECTOR, “QUINTON MARINE PLASMA”, IN EXPERIMENTS ON CULTURED CELLS. Vestnik Moskovskogo universiteta. Seriya 16. Biologiya. 2015;(1):9-13. (In Russ.) https://doi.org/10.1234/XXXX-XXXX-2015-1-9-13

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ISSN 0137-0952 (Print)