Structural defense mechanisms of parasitic larvae against host immune factors in Triaenophorus nodulosus (Cestoda)–perch interaction
https://doi.org/10.55959/MSU0137-0952-16-79-2-3
Abstract
Structural aspects of host-parasite interactions between Triaenophorus nodulosus – European perch have been studied. A number of structural mechanisms involved in defense reaction against host immunity were revealed. Plerocercoids were located inside the perch liver. As a response to the invasion, a parasitic granuloma develops around the parasite. The capsule wall was shown to consist of several layers of different tissue types. The outer fibrous layer contained fibroblasts and connective tissue fibres. The inner layer was composed of several rows of flattened epithelioid cells connected with each other by desmosomes. On the inner surface of the capsule wall, individual macrophages were found showing phagocytic activity. The observed structural differences of the capsule wall cells depend on invasion time and physiologic condition of the interactions. Phagocytosis of apical parts of microtriches by macrophages was first documented. Additionally, radial fibrous non-cellular structures of unknown origin were observed. The plerocercoid lying free in the capsule cavity possessed developed hooks covered by the tegument, in contrast to adult worms with uncovered hooks. The tegument releases a thick layer of filamentous matrix, extracellular vesicles, and vacuolized microtriches. Free terminals of different specialized cell types were found to release secretory products via three pathways: frontal glands, tumuli, neurosecretory cup-shaped terminals. Universal adaptations intrinsic to all developmental stages, and those characteristic of plerocercoids (e.g. vacuolized microtriches) were revealed.
Keywords
Bothriocephalidea,
glands,
secretory-excretory products,
tegument,
granuloma,
hostparasite interface
Supporting agencies: The research was funded by Russian Science Foundation, project number 23-24-00118.
About the Authors
I. A. Kolesnikov
Lomonosov Moscow State University
Russian Federation
Russian Federation
Department of Invertebrate Zoology, School of Biology,
Leninskie gory 1–12, Moscow, 119234
N. M. Biserova
Lomonosov Moscow State University
Russian Federation
Russian Federation
Department of Invertebrate Zoology, School of Biology,
Leninskie gory 1–12, Moscow, 119234
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Kolesnikov I.A., Biserova N.M. Structural defense mechanisms of parasitic larvae against host immune factors in Triaenophorus nodulosus (Cestoda)–perch interaction. Vestnik Moskovskogo universiteta. Seriya 16. Biologiya. 2024;79(2):112-120. (In Russ.) https://doi.org/10.55959/MSU0137-0952-16-79-2-3
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