On the nature of lengthy nucleotide repeated sequences in genomes of prokaryotic organisms
Abstract
The whole-genomic analysis in silico of 64 free-living prokaryotic species has been performed to determine the number, length, distribution and location of direct and inverted intragenomic repeated sequences (LRS). Three main types of lengthy ( 500 bp) repeated sequences were revealed: a) associated with ribosomal RNA genes; b) with copies of protein coding genes; c) with IS-elements and genes encoding putative transposases. Lengthy repeated sequences related to transposases comprise 50—95% of total number of LRS depending on species. Intragenomic LRS associated with transposases and IS-elements can reflect a recombinational potential of different prokaryotic species determining both the ability to adaptive gene rearrangements and cell capacity for integration of genes acquired through horizontal transfer ways.
About the Authors
L. E. Mikheeva
Lomosov Moscow State University
Russian Federation
Department of Genetics
Russian Federation
Department of Genetics
E. A. Karbysheva
Lomosov Moscow State University
Russian Federation
Department of Genetics
Russian Federation
Department of Genetics
S. V. Shestakov
Lomosov Moscow State University
Russian Federation
Department of Genetics
Russian Federation
Department of Genetics
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Review
For citations:
Mikheeva L.E., Karbysheva E.A., Shestakov S.V. On the nature of lengthy nucleotide repeated sequences in genomes of prokaryotic organisms. Vestnik Moskovskogo universiteta. Seriya 16. Biologiya. 2008;(1):14-22. (In Russ.)
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