Subcutaneous and visceral fat indices and their relationship with the complex of endogenous and exogenous factors in the group of adult population of the Altai Republic

The aim of the study was to analyze the association between complex of anthropogenetic and environmental factors with subcutaneous and visceral fat indices measured by local configurations of bioimpedance analysis in group of ethnic Altaians. In this study we examined whether anthropogenetic and environmental factors contributed to subcutaneous (SFI) and visceral fat indexes (FVI) measured by local configurations of bioimpedance analysis among ethnic Altaians. The study included 110 relatively healthy participants aged 17 to 35 years; 48 were female (44%). The examination program included anthropometric measurements, buccal swabs collection for genetic analysis (UCP1-3, rs1800592, rs660339, rs1800849) and body composition assessment by using bioelectrical impedance analysis (ABC-02 “Medass”), which was applied using a conventional whole-body «wrist-to-ankle» measurement configuration and two local measurement configurations in the abdominal region for the assessment of subcutaneous and visceral fat. Significant gender-related differences were found in the most morphological and functional characteristics. Maximal correlations were shown for subcutaneous and visceral fat indexes with WHtR and body fat percentage. Endogenous factors such as sex, age and genotype were not found to have significant effect on SFI and VFI in the examined group. Informative feature selection was performed by random forest and Boruta algorithm and WHtR and body fat percentage were revealed as the key predictors of abdominal fat deposition indexes.

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