Antioxidant activity of certain aquatic extracts used in traditional Chinese medicine
Abstract
In 2020, the Ministry of Health of China added Dendrobium officinale, Ganoderma lucidum, Gastrodia elata, Cornus officinalis, Eucommiae ulmoides, Cistanche deserticola, Astragalus membranaceus, Panax quinquefolium, Codonopsis pilosula to the list of approved medicinal plant raw materials. It was found that aqueous extracts of E. ulmoides, C. deserticola and C. officinalis have the overall values of the total antioxidant activity; and G. elata and D. officinale extracts were the least efficient among all tested plants. The performed regression analysis showed a correlation between the total content of phenolic compounds in the extracts and the total antioxidant activity (r=0.67, p=0.039). In all used test systems, E. ulmoides extract had the most effective antioxidant properties.
Keywords
traditional Chinese medicine,
water extracts,
antioxidant activity,
phenolic compounds,
oxidative stress,
reactive oxygen species,
free radicals
Supporting agencies: The research was funded by Shenzhen Science and Technology Innovation Committee (People’s Republic of China), project number 20200828172651001; also, this study was performed under the state assignment of Moscow State University, project number 121032500076-1, by Russian the Interdisciplinary Scientific and Educational School of Moscow State University «Molecular Technologies of the Living Systems and Synthetic Biology».
About the Authors
A. A. Bayzhumanov
Lomonosov Moscow State University, Department of Biophysics
Russian Federation
Russian Federation
School of Biology
1–12 Leninskie Gory, Moscow, 119234
L. Mai
Shenzhen MSU–BIT University
China
China
School of Biology
Ruyi Rd. 299, Longgang district, 518172, Shenzhen, Guangdong province
A. I. Yusipovich
Lomonosov Moscow State University, Department of Biophysics
Russian Federation
Russian Federation
School of Biology
1–12 Leninskie Gory, Moscow, 119234
G. V. Maksimov
Lomonosov Moscow State University, Department of Biophysics
Russian Federation
Russian Federation
School of Biology
1–12 Leninskie Gory, Moscow, 119234
References
1. Pizzino G., Irrera N., Cucinotta M., Pallio G., Mannino F., Arcoraci V., Squadrito F., Altavilla D., Bitto A. Oxidative stress: Harms and benefits for human health // Oxid. Med. Cell Longev. 2017. Vol. 2017: 8416763.
2. Fraga C.G., Croft K.D., Kennedy D.O., Tomás-Barberán F.A. The effects of polyphenols and other bioactives on human health // Food Funct. 2019. Vol. 10. N 2. P. 514–528.
3. Kushi L.H., Folsom A.R., Prineas R.J., Mink P.J., Wu Y., Bostick R.M. Dietary antioxidant vitamins and death from coronary heart disease in postmenopausal women // N. Engl. J. Med. 1996. Vol. 334. N 18 P. 1156–1162.
4. Park H.A., Ellis A.C. Dietary antioxidants and Parkinson’s disease // Antioxidants (Basel, Switzerland). 2020. Vol. 9. N 7: 570.
5. Scalbert A., Manach C., Morand C., Rémésy C., Jiménez L. Dietary polyphenols and the prevention of diseases // Crit. Rev. Food Sci. Nutr. 2005. Vol. 45 N 4. P. 287–306.
6. Zheng W., Wang S.Y. Antioxidant activity and phenolic compounds in selected herbs // J. Agric. Food Chem. 2001. Vol. 49. N 11. P. 5165–5170.
7. He F., Chen J., Dong K., Leng Y., Xu J., Hu P., Yao Y., Xiong J., Pei X. Multi-technical analysis on the antioxidative capacity and total phenol contents of 94 traditional Chinese dietary medicinal herbs // Food Sci. Nutr. 2018. Vol. 6. N 6. P. 1358–1369.
8. Garjani A., Tila D., Hamedeyazdan S., Vaez H., Rameshrad M., Pashaii M., Fathiazad F. An investigation on cardioprotective potential of Marrubium vulgare aqueous fraction against ischaemia-reperfusion injury in isolated rat heart // Folia Morphol. (Warsz). 2017. Vol. 76. N 3. P. 361–371.
9. Pankratova M.S., Baizhumanov A.A., Yusipovich A.I., Faassen M., Shiryaeva T.Y., Peterkova V.A., Kovalenko S.S., Kazakova T.A.., Maksimov GV. Imbalance in the blood antioxidant system in growth hormone-deficient children before and after 1 year of recombinant growth hormone therapy // PeerJ. 2015: e1055
10. Agil A., Fuller C.J, Jialal I. Susceptibility of plasma to ferrous iron/hydrogen peroxide-mediated oxidation: demonstration of a possible Fenton reaction // Clin. Chem. 1995. Vol. 41. N 2. P. 220–225.
11. Матюлько И.С., Байжуманов А.А., Хиразова Е.Э., Маслова М.В. Влияние различных режимов питьевой депривации на систему антиоксидантной защиты крови и поведенческую активность крыс // Журн. мед.-биол. исслед. 2018. Т. 6. № 3. С. 254–261.
12. Ramkissoon J.S., Mahomoodally M.F., Ahmed N., Subratty A.H. Relationship between total phenolic content, antioxidant potential, and antiglycation abilities of common culinary herbs and spices // J. Med. Food. 2012. Vol. 15. N 12. P. 1116–1123.
13. Владимиров Ю.А., Проскурина Е.В. Свободные радикалы и клеточная хемилюминесценция // Усп. биол. химии. 2009. Т. 49. № 7. С. 341–388.
Review
For citations:
Bayzhumanov A.A., Mai L., Yusipovich A.I., Maksimov G.V. Antioxidant activity of certain aquatic extracts used in traditional Chinese medicine. Vestnik Moskovskogo universiteta. Seriya 16. Biologiya. 2022;77(1):16-21. (In Russ.)
Views:
320
Email this article 