SPONTANEOUS AND EVOKED CALCIUM OSCILLATIONS IN ASTROCYTES OF HIPPOCAMPUS SLICE
https://doi.org/10.1234/XXXX-XXXX-2011-2-13-15
Abstract
In this work we researched Ca2+ oscillations in astrocytes of hippocampus acute slices, using confocal laser scanning microscopy and bulk-loading of the Ca2+-sensitive dye Oregon Green Bapta 1-AM. We demonstrated that frequency and duration of the calcium oscillations had reduced by the rat age, but frequency and duration of the calcium oscillations had increased by the glutamate application.
About the Authors
Y. I. KalintsevaRussian Federation
A. V. Potanina
Russian Federation
A. S. Pimashkin
Russian Federation
Yu. Yu.N. Zaharov
Russian Federation
I. V. Mukhina
Russian Federation
V. B. Kazantsev
Russian Federation
A. V. Semyanov
Russian Federation
References
1. Agulhon C., Petravicz J., McMullen, etc. What is the role of astrocyte calcium in neurophysiology? // Neuron. 2008. Vol. 59. P. 932—946.
2. Fiacco T.A., McCarthy K.D. Astrocyte calcium elevations: properties, propagation, and effects on brain signaling // Glia. 2006. Vol. 54. P. 676—690.
3. Nieden R.Z., Deitmer W. The role of metabotropic glutamate receptos for the generation of calcium oscillations in rat hippocampal astrocytes in situ // Cerebral Cortex. 2006. Vol. 16. P. 676—687.
4. Vannucci1 S.J., Simpson I.A. Developmental switch in brain nutrient transporter expression in the rat // Amer. Phy- siol. Soc. 2003. Vol. 18. P. 1127—1134.
Review
For citations:
Kalintseva Y.I., Potanina A.V., Pimashkin A.S., Zaharov Yu.Yu., Mukhina I.V., Kazantsev V.B., Semyanov A.V. SPONTANEOUS AND EVOKED CALCIUM OSCILLATIONS IN ASTROCYTES OF HIPPOCAMPUS SLICE. Vestnik Moskovskogo universiteta. Seriya 16. Biologiya. 2011;(2):13-15. (In Russ.) https://doi.org/10.1234/XXXX-XXXX-2011-2-13-15