MOLECULAR MECHANISMS OF TRANSCRIPTION THROUGH CHROMATIN BY RNA POLYMERASE III
https://doi.org/10.1234/XXXX-XXXX-2012-3-6-11
Abstract
Chromatin is designed to tightly package DNA into the eukaryotic nucleus while maintaining its proper functioning. This review describes the mechanisms by which RNA polymerase III transcribes through the chromatin templates. This mechanism is characteristic of eukaryotic Pol III, bacteriophage RNA polymerases, and probably ATP-dependent chromatin remodeling complexes. In this case, nucleosomes are translocated without release of the octamer into solution.
About the Authors
V. M. Studitsky
Department of Pharmacology, University of Medicine and Dentistry of New Jersey, 675 Hoes Lane, Room 405, Piscataway, NJ 08854,USA
Russian Federation
Russian Federation
I. V. Orlovsky
Russian Federation
O. V. Chertkov
Russian Federation
N. S. Efimova
Russian Federation
M. A. Loginova
Russian Federation
O. I. Kulaeva
Department of Pharmacology, University of Medicine and Dentistry of New Jersey, 675 Hoes Lane, Room 405, Piscataway, NJ 08854,USA
Russian Federation
Russian Federation
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Review
For citations:
Studitsky V.M., Orlovsky I.V., Chertkov O.V., Efimova N.S., Loginova M.A., Kulaeva O.I. MOLECULAR MECHANISMS OF TRANSCRIPTION THROUGH CHROMATIN BY RNA POLYMERASE III. Vestnik Moskovskogo universiteta. Seriya 16. Biologiya. 2012;(3):6-11. (In Russ.) https://doi.org/10.1234/XXXX-XXXX-2012-3-6-11
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