INVESTIGATION OF PROTECTIVE PROPERTIES OF SHIGELLA SONNEI CARBOHYDRATE BIOPOLYMERS UNDER EXPERIMENTAL ENDOTOXIC SHOCK MODELS
https://doi.org/10.1234/XXXX-XXXX-2013-2-12-15
Abstract
Study tolerogenic properties of new non-pyrogenic low-endotoxic complex preparation composed of Shigella sonnei carbohydrate biopolymers under D-galactosamine and direct experimental endotoxic shock models. Pretreatment with complex preparation protects mice (CBA Ѕ C57Bl/6)F1 against lipopolysaccharide (E. coli O:55) — mediated death. We demonstrate correlation between increasing pre-immunization dose of complex preparation with rate of survival and reduction of TNF-a serum level under direct endotoxic shock model.
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For citations:
Markina A.A., Kondratieva I.A. INVESTIGATION OF PROTECTIVE PROPERTIES OF SHIGELLA SONNEI CARBOHYDRATE BIOPOLYMERS UNDER EXPERIMENTAL ENDOTOXIC SHOCK MODELS. Vestnik Moskovskogo universiteta. Seriya 16. Biologiya. 2013;(2):12-15. (In Russ.) https://doi.org/10.1234/XXXX-XXXX-2013-2-12-15
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